Adolescent Idiopathic Scoliosis progression when mediated by medicinal and bracing intervention
Date of Award
Spring 5-10-2026
Document Type
Thesis
Degree Name
Master of Science in Orthotics and Prosthetics
Department
Kinesiology
First Advisor
Amy Funke
Abstract
Adolescent idiopathic scoliosis (AIS), poses a complex challenge with a lateral spinal curvature, as measured by the Cobb angle. Long standing methods of stopping AIS progression such as rigid bracing face limitations that this research hoped to address. Recent research has indicated that the etiology of AIS is far more complex than simply being a dysfunction in one’s musculoskeletal systems. This research explored a modern intervention that combined neurotransmitter regulation with nighttime bracing to mitigate or reduce Cobb angle progression in AIS patients. This study integrated quantitative assessments of changes in Cobb angle and changes in neurotransmitter levels. By addressing potential neurotransmitter imbalances associated with AIS and providing mechanical support through nighttime bracing, this research aimed to deliver a holistic and efficient treatment strategy, that provides a non-invasive treatment option. The implications of this study could pave the way for more comprehensive and personalized treatment protocols for AIS, offering promising avenues for future research and clinical practice.