Effect of Passive Torso Support on Breathing Kinematics in Non-Ambulatory DMD Patients

Date of Award

Spring 5-2025

Document Type

Non Thesis

Degree Name

Master of Science in Orthotics and Prosthetics

Department

Kinesiology

First Advisor

Amy Funke

Abstract

The proposed study investigated the impact of a novel semi-custom orthosis (passive trunk support system) on breathing kinematics in non-ambulatory late-stage Duchenne muscular dystrophy (DMD) patients. Using Optoelectronic Plethysmography (OEP), observed differences in thoracic compartment utilization, abdominal compartment utilization, and tidal volume capacity (TVC) were measured before and after orthotic intervention. Involving 20 non-ambulatory DMD patients, the study utilized OEP to measure total chest wall and compartmental volumes before and after implementing the orthosis. Positive impact on these metrics could have increased respiratory function or improved efficacy of other respiratory treatments, with the goal of improving length and quality of life for patients. Further data on the interplay of orthotic intervention and respiratory function for DMD patients were needed to establish a stronger consensus around treatment best practices.

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