Evaluating the Use of the Ottobock C-Brace® for Restoration of Gait in Adrenomyeloneuropathy
Date of Award
Spring 5-3-2025
Document Type
Non Thesis
Degree Name
Master of Science in Orthotics and Prosthetics
Department
Kinesiology
First Advisor
Amy Funke
Abstract
Adrenomyeloneuropathy (AMN) is an X-linked neurodegenerative disorder that results in progressive axonal demyelination and disturbances to gait and mobility. This proposal aims to investigate the effectiveness of the Ottobock C-Brace as an intervention for improving mobility and restoring natural gait patterns in individuals with advanced AMN. A comprehensive methodology will be proposed involving the collection of kinematic gait data using the Vicon motion capture system, along with performance-based and patient-reported outcome measures. Proposed participants include individuals with confirmed AMN diagnosis and an Expanded Disability Status Scale (EDSS) score of 4.0 to 6.5. The study will employ a pre-post intervention design, with participants undergoing a six-week training period followed by six weeks of independent use of bilateral C-Braces. Data analysis will compare pre- and post-intervention outcomes, with practical applications including refinement of treatment protocols, advancement of research, and advocacy for increased resources and insurance coverage. Regardless of the outcomes if this study were to be conducted, this proposal provides valuable insights into alternative interventions and highlights the need for further research to address the complex needs of AMN patients.